Table 4.

Candidate variables significant on univariate and multivariate analyses of characteristics predicting local control

Characteristic	Univariate			Multivariate
	HR	95% CI	P	HR	95% CI	P
Isodose	0.93	0.896-0.974	.001	0.953	0.911-0.996	.031
Tumor volume (mm3)	1.57	1.40-1.759	<.001	1.359	1.197-1.543	<.001
V32	0.06	0.018-0.175	<.001	0.069	0.018-0.264	<.001
Prior WBRT	1.90	1.33-2.717	<.001
WBRT within 2 months	1.87	1.03-3.407	.039
Perfexion model	0.59	0.357-0.985	.043
Dose (Gy)	0.81	0.74-0.883	<.001
Number of shots	1.12	1.08-1.151	<.001
CI	0.75	0.611-0.913	.004
Dmean	1.00	0.998-0.999	<.001
Dmedian	1.00	0.998-0.999	<.001
Dmin	1.00	0.998-0.999	<.001
D10	1.00	0.999-1.00	<.001
D50	1.00	0.998-0.999	<.001
D90	1.00	0.997-0.999	<.001
V18	0.04	0.007-0.255	<.001
V20	0.11	0.04-0.301	<.001
V21	0.16	0.07-0.330	<.001
V22	0.20	0.107-0.355	<.001
V23	0.19	0.107-0.321	<.001
V24	0.19	0.108-0.321	<.001
V25	0.19	0.107-0.322	<.001
V26	0.19	0.106-0.329	<.001
V27	0.17	0.092-0.310	<.001
V28	0.16	0.084-0.310	<.001
V29	0.14	0.068-0.291	<.001
V30	0.13	0.055-0.280	<.001
V31	0.09	0.035-0.229	<.001
V33	0.03	0.008-0.135	<.001
V34	0.02	0.003-0.105	<.001
V35	0.01	0.001-0.075	<.001
V36	0.00	0.000-0.064	<.001
V37	0.00	0.000-0.042	<.001
V38	0.00	0.000-0.020	.001
V39	0.00	0.000-0.009	.007

Abbreviations as in Table 1, Table 3.

Bold text indicates statistical significance.