2.
NSCLC中AQP3的表达及与临床病理特征的关系
AQP3 expression and clinicopathological factors in NSCLC
| n | AQP3 | χ2 | P | |||
| (-) (n=25) | (+) (n=67) | (++) (n=88) | ||||
| Age (yr) | 0.558 | 0.756 | ||||
| < 60 | 82 | 13 (15.8%) | 29 (35.4%) | 40 (48.8%) | ||
| ≥60 | 98 | 12 (12.2%) | 38 (38.8%) | 48 (49.0%) | ||
| Gender | 11.595 | 0.003 | ||||
| Male | 117 | 15 (12.8%) | 37 (31.6%) | 65 (55.6%) | ||
| Female | 63 | 10 (15.9%) | 30 (47.6%) | 23 (36.5%) | ||
| Histological type | 67.836 | < 0.001 | ||||
| Squamous cell carcinoma | 64 | 6 (9.3%) | 35 (54.7%) | 23 (36.0%) | ||
| Adenocarcinoma | 99 | 5 (5.0%) | 29 (29.2%) | 65 (65.7%) | ||
| Large cell | 10 | 8 (80.0%) | 2 (20.0%) | 0 | ||
| Others | 7 | 6 (85.7%) | 1 (14.3%) | 0 | ||
| Lymph node metastasis | 7.301 | 0.026 | ||||
| Absent | 53 | 8 (15.1%) | 27 (51.0%) | 18 (33.9%) | ||
| Present | 127 | 17 (13.4%) | 40 (31.5%) | 70 (55.1%) | ||
| Tumor cell differentiation | 33.559 | < 0.001 | ||||
| Well-moderately differentiated | 109 | 8 (7.3%) | 29 (26.6%) | 72 (66.1%) | ||
| Poorly differentiated | 71 | 17 (23.9%) | 38 (53.5%) | 16 (22.6%) | ||
| Pathological stage (TNM) | 0.409 | 0.815 | ||||
| Ⅰ/Ⅱ | 104 | 13 (10.0%) | 39 (35.0%) | 52 (55.0%) | ||
| Ⅲ | 76 | 12 (15.8%) | 28 (36.8%) | 36 (47.4%) | ||