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NSCLC中VM、CD82/KAI1、HIF-1α和MVD的表达与临床病理因素的关系

Correlation of VM and CD82/KAI1 and HIF-1α and MVD expression to clinicopathologic characteristics in NSCLC

Variable	VM		χ2	CD82/KAI1		χ2	HIF-1α		χ2	MVD		χ2
	-	+		-	+		-	+		< 22	≥22
*P < 0.05, #P < 0.01.
Gender			1.521			1.849			3.143			4.287*
Male	85	45		78	52		71	59		79	51
Female	16	14		22	8		11	19		12	18
Age (yr)			0.317			0.168			0.433			0.870
< 60	45	29		45	29		40	34		45	29
≥60	56	30		55	31		42	44		46	40
Gross type			2.014			0.569			0.834			0.008
Central	72	48		73	47		59	61		68	52
Peripheral	29	11		27	13		23	17		23	17
Histological type			0.424			0.301			0.038			1.170
Squamous cell carcinoma	75	41		71	45		60	56		69	47
Adenocarcinoma	26	18		29	15		22	22		22	22
Diameter (cm)			0.069			0.044			0.139			0.066
< 3.0	9	6		9	6		7	8		9	6
≥3.0	92	53		91	54		75	70		82	63
Differentiation			33.816#			33.944#			19.128#			20.066#
Well	20	1		2	19		19	2		19	2
Mediate	72	31		67	36		52	51		61	42
Poor	9	27		31	5		11	25		11	25
Lymph node metastasis			31.025#			14.142#			36.023#			30.318#
Yes	31	45		41	43		20	56		26	50
No	70	14		59	17		62	22		65	19
PTNM stage			63.712#			48.439#			97.173#			85.686#
Ⅰ-Ⅱ	71	3		25	49		69	5		71	3
Ⅲ-Ⅳ	30	56		75	11		13	73		20	66