4.
单因素分析影响老年广泛期SCLC患者生存期的相关因素
Single analysis for survival of the ED-SCLC in the elderly
| Factor | n (%) | MST (month) | 95%CI (month) | P | |
| Total | 115 | 11 | 9.6-12.4 | ||
| Sex | Male | 85 (73.9) | 9 | 7.2-10.8 | 0.002 |
| Female | 30 (26.1) | 16 | 11.0-21.0 | ||
| Age (yr) | 65-75 | 98 (85.2) | 11 | 9.6-12.4 | 0.155 |
| ≥75 | 17 (14.8) | 8 | 5.6-10.4 | ||
| PS before treatment (ECOG) | 0 | 4 (3.5) | 10 | 3.1-16.9 | 0.523 |
| 1 | 82 (71.3) | 10 | 7.7-12.3 | ||
| 2 | 23 (20.2) | 11 | 10.2-11.8 | ||
| 3 | 6 (5.2) | 8 | 3.2-12.8 | ||
| The change of PS after treatment | Improve | 56 (48.7) | 11 | 9.1-12.9 | ＜0.001 |
| Stable | 41 (35.7) | 12 | 9.9-14.1 | ||
| Worsen | 18 (15.6) | 4 | 3.0-5.0 | ||
| Chemotherapy scheme | EP or EC | 94 (81.7) | 11 | 9.6-12.4 | 0.007 |
| Not EP or EC | 21 (18.3) | 8 | 5.3-10.7 | ||
| Liver | Yes | 29 (25.2) | 7 | 5.0-9.0 | 0.001 |
| No | 86 (74.8) | 12 | 10.1-13.9 | ||
| Lung | Yes | 40 (34.8) | 10 | 8.3-11.7 | 0.396 |
| No | 75 (65.2) | 11 | 9.1-12.9 | ||
| Brain | Yes | 24 (20.9) | 8 | 6.1-9.9 | 0.063 |
| No | 91 (79.1) | 11 | 9.6-12.4 | ||
| Abdomen | Yes | 32 (27.8) | 10 | 7.8-12.2 | 0.073 |
| No | 83 (72.2) | 11 | 8.9-13.1 | ||
| Bone | Yes | 28 (24.3) | 9 | 6.4-11.6 | 0.087 |
| No | 87 (75.7) | 11 | 9.5-12.5 | ||
| Radiotherapy | Yes | 50 (56.8) | 14 | 10.7-17.3 | < 0.001 |
| No | 38 (43.2) | 10 | 8.1-11.9 | ||
| Radiotherapy （< 2 organ metastasis） |
Yes No |
40 (66.7) 20 (33.3) |
16 8 |
12.7-19.3 5.8-10.2 |
< 0.001 |
| Radiotherapy (≥2 organ metastasis） |
Yes No |
10 (35.7) 18 (64.3) |
9 11 |
7.5-10.5 10.1-12.0 |
0.891 |
| PCI | Yes | 12 (24.0) | 23 | 16.6-29.4 | 0.01 |
| No | 38 (76.0) | 12 | 10.7-13.3 |