1.
手术患者术前临床特点
Clinical characteristics of surgical patients before operation
| Characteristics | Value |
| UFC: urinary free cortisol; ACTH: adrenocorticotropic hormone; LDDST: low doses of dexamethasone test; HDDST: high doses of dexamethasone test; IPSS: inferior petrosal sinus sampling; CT: computed tomography; MRI: magnetic resonance image. | |
| Median age (yr) | 29.0 (13-46) |
| Male/Female | 1.33:1 (8:6) |
| Median duration (mo) | 4 (1-44) |
| Symptom and sign | |
| Hypertesion | 8/14 (57.1%) |
| Facial plethora | 10/14 (71.4%) |
| Central obesity | 9/14 (64.3%) |
| Moon face | 10/14 (71.4%) |
| Buffalo bump | 10/14 (71.4%) |
| Proximal muscle weakness | 8/14 (57.1%) |
| Biological data | |
| Hyperglycemia | 9/14 (64.3%) |
| Hypokalemia | 13/14 (92.8%) |
| Serum cortisol elevation | 14/14 (100.0%) |
| UFC elevation | 14/14 (100.0%) |
| Plasma ACTH elevation | 14/14 (100.0%) |
| LDDST negative | 14/14 (100.0%) |
| HDDST negative | 13/14 (92.8%) |
| IPSS no centroperipheral gradient | 4/4 (100.0%) |
| Imaging | |
| Abnormal pituitary MRI or CT | 3/14 (21.4%) |
| Abnormal adrenal gland CT scan | 14/14 (100.0%) |
| Thoracic CT detection tymic mass | 14/14 (100.0%) |
| 111In-octreotide scintigraphy | 6/7 (86%) |
| Unnecessary surgical intervention | |
| Adrenalectomy | 2/14 (14.3%) |
| Hypophysectomy | 2/14 (14.3%) |
| Saddle area radiotherapy | 1/14 (7.1%) |