2.

纳入研究的23篇文献的质量评价(STROBE声明)

STROBE Statement-checklist criteria of 23 reports included in this study

Items	Recommendation	Number of stydy
Title and abstract	1.1 Indicate the study’s design with a commonly used term in the title or the abstract	23 (100%)
	1.2 Provide in the abstract an informative and balanced summary of what was done and what was found	23 (100%)
Introduction
Background/Rationale	2 Explain the scientific background and rationale for the investigation being reported	23 (100%)
Objectives	3 State specific objectives, including any prespecified hypotheses	23 (100%)
Methods
Stydy desin	4 Present key elemens of study design early in the paper	23 (100%)
Setting	5 Describe the setting, locations, and relevant dates, including periods of recruitment, exposure, follow-up, and data collection	23 (100%)
Participants	6.1 Give the eligibility criteria, and the sources and methods of ascertainment, and control selection.Give the rationale for the choice of cases and controls	18 (78.3%)
	6.2 For matched studies, give matching criteria and the number of controls per case	12 (52.2%)
Variables	7 Clearly define all outcomes, exposures, predictors, potential confounders, and effect modifiers. Give diagnostic criteria, if applicable	11 (47.8%)
Datasources/Measurement	8 For each variable of interest, give sources of data and details of methods of assessment (measurement). Describe comparability of assessment methods if there is more than one group	10 (43.5%)
Bias	9 Describe any efforts to address potential sources of bias	3 (13%)
Study size	10 Explain how the study size was arrived at	0 (0)
Quantitative variables	11 Explain how quantitative variables were handled in the analyses. If applicable, describe which groupings were chosen and why	5 (21.7%)
Statistical methods	12.1 Describe all statistical methods, including those used to control for confounding	20 (87%)
	12.2 Describe any methods used to examine subgroups and interactions	12 (52.2%)
	12.3 Explain how missing data were addressed	8 (34.8%)
	12.4 If applicable, explain how matching of cases and controls was addressed	7 (30.4%)
	12.5 Describe any sensitivity analyses	7 (30.4%)
Results
Participants	13.1 Report numbers of individuals at each stage of study—eg numbers potentially eligible, examined for eligibility, confirmed eligible, included in the study, completing follow-up, and analysed	20 (87%)
	13.2 Give reasons for non-participation at each stage	4 (17.4%)
	13.3 Consider use of a flow diagram	0 (0)
Descriptive data	14.1 Give characteristics of study participants (eg demographic, clinical, social) and information on exposures and potential confounders	18 (78.3%)
	14.2 Indicate number of participants with missing data for each variable of interest	5 (21.7%)
Outcome data	15 Report numbers in each exposure category, or summary measures of exposure	15 (65.2%)
	16.1 Give unadjusted estimates and, if applicable, confounder-adjusted estimates and their precision (eg, 95% confidence interval). Make clear which confounders were adjusted for and why they were included	14 (60.9%)
	16.2 Report category boundaries when continuous variables were categorized	17(73.9%)
	16.3 If relevant, consider translating estimates of relative risk into absolute risk for a meaningful time period	3 (13%)
Other analyses	17 Report other analyses done—eg analyses of subgroups and interactions, and sensitivity analyses	5 (21.7%)
Discusion
Key results	18 Summarise key results with reference to study objectives	23 (100%)
Limitations	19 Discuss limitations of the study, taking into account sources of potential bias or imprecision. Discuss both direction and magnitude of any potential bias	14 (60.9%)
Interpretation	20 Give a cautious overall interpretation of results considering objectives, limitations, multiplicity of analyses, results from similar studies, and other relevant evidence	21(91.3%)
Generalisability	21 Discuss the generalisability (external validity) of the study results	19 (82.6%)
Other information
Funding	22 Give the source of funding and the role of the funders for the present study and, if applicable, for the original study on which the present article is based	15(65.2%)