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Ⅲ-Ⅳ级毒性反应（n=66）
Toxicities of grade Ⅲ-Ⅳ (n=66)
| Toxicity | GO group (n =33) | GP group (n =33) | P |
| Leukopenia | 2 (6.1%) | 3 (9.1%) | > 0.999 |
| Thrombocytopenia | 5 (15.2%) | 4 (12.1%) | > 0.999 |
| Anemia | 0 | 11 (33.3%) | < 0.001 |
| Nausea/vomiting | 0 | 9 (27.3%) | 0.004 |
| Impaired liver function | 0 | 0 | |
| Impaired renal function | 0 | 0 | |
| Neurotoxicity | 0 | 0 | |
| Rash | 0 | 1 (3.0%) | > 0.999 |
