2.

先证者一级亲属患癌风险

Risk of cancer in first-degree relatives of proband

Factor	Case/Control	Crude OR (95%CI)	Adjusted ORa (95%CI)
a: ORs calculated by conditional logistic regression adjusted for sex, lung disease history, smoking status, living environment and occupation expose.
Proband’s family history
No	432/438	1.00	1.00
Yes	201/127	1.60 (1.24-2.08)	1.71 (1.28-2.28)
N of families with
0	432/438	1.00	1.00
1	149/111	1.36 (1.03-1.80)	1.55 (1.14-2.12)
2+cancers	52/16	3.30 (1.85-5.86)	2.65 (1.42-4.94)