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115例三线治疗Ⅲb期/Ⅳ期肺癌患者的Ⅲ度-Ⅳ度毒性反应
The toxic side effects of 115 stage Ⅲb/Ⅳ lung cancer patients receiving third-line therapy
| Toxic side effects | EGFR-TKIs (n=44) | Single agent (n=39) | Doublet agent (n=32) | P | |||||
| Ⅲ | Ⅳ | Ⅲ | Ⅳ | Ⅲ | Ⅳ | ||||
| Hematologic | 0 | 0 | 6 | 1 | 9 | 6 | < 0.001 | ||
| Digestive | 2 | 0 | 3 | 0 | 2 | 0 | 0.835 | ||
| Diarrhea | 2 | 0 | 1 | 0 | 2 | 0 | 0.241 | ||
| Hepatic and renal | 0 | 0 | 1 | 0 | 1 | 0 | 0.524 | ||
| Fatigue | 0 | 0 | 1 | 0 | 1 | 0 | 0.337 | ||
| Rash | 3 | 1 | 0 | 0 | 0 | 0 | 0.570 | ||
| Fever with neutrophils | 0 | 0 | 0 | 0 | 0 | 1 | 0.270 | ||
