4.

非铂双药与单药化疗的3/4级毒副反应

Comparison of grade 3/4 toxicity between non platinum-based doublet arms and single-agent arms in trials

Toxicity	No. of trials	No. of patients		OR	95%CI	P
		Doublet arms	Single-agent arms
Anemia	8	932	926	1.13	0.56-2.30	0.728
Neutropenia	8	932	926	1.28	0.78-2.10	0.324
Thrombocytopenia	8	932	926	1.74	0.88-3.43	0.110
Nausea & vomiting	8	932	926	0.99	0.58-1.70	0.980
Neurotoxicity	7	872	866	1.11	0.44-2.82	0.825