1.
长期生存者人口学和临床特征
Demography and clinical characteristics of long-term survivors
| Active long-term survivor (n=25) | Long-term survivor terminated from EAP (n=34) | Total (n=59) | |
| Age (year) | |||
| Median | 58.4 | 52.45 | 56.6 |
| Missing | 1 | 4 | 5 |
| Age distribution [n (%)] | |||
| < 65 years | 15 (62.50) | 22 (73.33) | 37 (68.52) |
| ≥65 years | 9 (37.50) | 8 (26.67) | 17 (31.48) |
| Missing | 1 | 4 | 5 |
| Sex, n(%) | |||
| Fem ale | 14 (56.00) | 19 (55.88) | 33 (55.93) |
| Male | 11 (44.00) | 15 (44.12) | 26 (44.07) |
| Pathology [n (%)] | |||
| Squamous carcinoma | 3 (12.00) | 1 (2.94) | 4 (6.78) |
| Adenocarcinoma | 17 (68.00) | 31 (91.18) | 48 (81.36) |
| Bronchiolo alveolar carcinoma | 4 (16.00) | 2 (5.88) | 6 (10.17) |
| Others | 1 (4.00) | 0 | 1(1.69) |
| Smoking history [n (%)] | |||
| Never smoker | 17 (68.00) | 24 (72.73) | 41(70.69) |
| Ever smoker | 8 (32.00) | 8 (24.24) | 16(27.59) |
| Smoker | 0 | 1 (3.03) | 1(1.72) |
| Missing | 0 | 1 | 1 |
| Stage [n (%)] | |||
| Ⅰ, Ⅱ | 2 (8.00) | 1 (3.33) | 3(5.45) |
| Ⅲ, Ⅳ | 23 (92.00) | 29 (96.67) | 52 (94.55) |
| Missing | 0 | 4 | 4 |
| Previous treatment [n (%)] | |||
| No | 0 | 4 (11.76) | 4 (6.78) |
| Yes | 25 (100.00) | 30 (88.24) | 55 (93.22) |
| Previous operation [n (%)] | |||
| No | 9 (36.00) | 16 (47.06) | 25 (42.37) |
| Yes | 16 (64.00) | 18 (52.94) | 34 (57.63) |
| Previous chemotherapy [n (%)] | |||
| No | 2 (8.00) | 4(12.12) | 6 (10.34) |
| Yes | 23 (92.00) | 29 (87.88) | 52 (89.66) |
| Missing | 0 | 1 | 1 |
| Previous radiotherapy [n (%)] | |||
| No | 12 (48.00) | 18 (54.55) | 30 (51.72) |
| Yes | 13 (52.00) | 15 (45.45) | 28 (48.28) |
| Missing | 0 | 1 | 1 |
| Compliance | |||
| Median | 0.97 | 1 | 1 |
| Compliance [n (%)] | |||
| > 120 | 0 | 0 | 0 |
| 80-120 | 24 (96.00) | 32 (94.12) | 56 (94.92) |
| < 80 | 1 (4.00) | 2 (5.88) | 3 (5.08) |
| Chemotherapy in EAP [n (%)] | |||
| No | 22 (88.00) | 22 (68.75) | 44 (77.19) |
| Yes | 3 (12.00) | 10 (31.25) | 13 (22.81) |
| Missing | 0 | 2 | 2 |
| Radiotherapy in EAP [n (%)] | |||
| No | 23 (95.83) | 24 (75.00) | 47 (83.93) |
| Yes | 1 (4.17) | 8 (25.00) | 9 (16.07) |
| Missing | 1 | 2 | 3 |
| Targeted therapy (only taken gefitinib in EAP) [n (%)] | |||
| No | 24 (96.00) | 27(87.10) | 51 (91.07) |
| Yes | 1 (4.00) | 4(12.90) | 5 (8.93) |
| Missing | 0 | 3 | 3 |
| Treatment in EAP [n (%)] | |||
| No | 22 (88.00) | 19 (59.38) | 41 (71.93) |
| Yes | 3 (12.00) | 13 (40.62) | 16 (28.07) |
| Missing | 0 | 2 | 2 |