3.

甘氨双唑钠联合放疗与单纯放疗或放疗联合安慰剂（维生素C）安全性比较的Meta分析

Meta-analysis of safety for CMNa plus radiotherapy

Adverse effects	Included studies	Treatment			Control			Heterogeneity
		n	N		n	N		I2	P
CMNa: metronidazole amino acidum natrium
Radiation esophagitis	8[5, 8, 10, 16, 18, 21, 23, 25]	119	273		120	254		0	0.99
Radiation pneumonitis	7[5, 8, 10, 16, 21, 23, 25]	78	241		76	231		0	0.99
Hematologic toxicit（myelosuppression）	7[5, 10, 16, 18, 21, 23, 25]	63	284		59	276		0	0.95
Radiodermatitis	3[10, 22, 25]	80	145		75	145		0	0.90
Weight loss	2[22, 25]	58	100		60	100		-	-
Liver and kidney	2[6, 22]	6	84		10	84		0	0.41
Heart	4[5, 6, 22, 23]	18	167		19	164		0	0.76
Nausea and vomiting	1[18]	4	32		4	32		-	-