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. 2015 Nov 20;18(11):686–690. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2015.11.05

2.

EGFRKRAS基因突变检测结果(n=395)

Results of EGFR and KRAS mutation status (n=395)

Item n Proportion (%)
EGFR gene
  Exton 18 (G719X) 10 2.5
  Exton 19 (19del) 93 23.5
  Exton 21 81 20.5
    L858R 73 18.5
    L861Q 6 1.5
    L858R2 2 0.5
  Exton 20 4 1.0
    T790M 1 0.3
    S768I 3 0.7
  Combination of two mutations 4 1.0
    21L858R+20T790M 1 0.3
    18G719+20S768I 1 0.3
    19del+21L858R 1 0.3
    21L858R+20S768I 1 0.3
  Wild type 202 51.1
  Failed screening 1 0.3
KRAS gene
  Mutation 29 7.3
    Exton 2 27 6.8
    Exton 3 2 0.5
  Wild type 364 92.2
  Failed screening 2 0.5
Combination of EGFR and KRAS mutations 1 0.3