1.
Trial | No. of patients | Timing (Early/Late) | OS (%) | Age range | PS | 2/3 year survival rate | OR | 95%CI |
Murry (1993) | 155 | E | 68 | NR | ECOG 0-1:87% | 40% | 0.77 | 0.49-1.23 |
153 | L | NR | ECOG 0-1:90% | 34% | ||||
Jeremic (1997) | 52 | E | 64 | 40-67 | KPS 90-100:52% | 71% | 0.46 | 0.20-1.03 |
51 | L | 44-66 | KPS 90-100:47% | 53% | ||||
Work (1997) | 99 | E | 66 | 36-70 | KPS 80-100:82% | 20% | 0.87 | 0.43-1.76 |
100 | L | 36-69 | KPS 80-100:80% | 18% | ||||
Perry (1998) | 125 | E | 70 | 32-79 | ECOG 0-1:86% | 18% | 1.97 | 1.10-3.53 |
145 | L | 32-79 | ECOG 0-1:87% | 30% | ||||
Skarlos (2001) | 42 | E | 58 | 40-76 | ECOG 0-1:76% | 36% | 0.71 | 0.28-1.81 |
39 | L | 38-79 | ECOG 0-1:85% | 28% | ||||
Takada (2002) | 114 | E | 67 | 39-74 | ECOG 0-1:95% | 54% | 0.45 | 0.27-0.77 |
114 | L | 30-74 | ECOG 0-1:95% | 35% |