. 2014 Nov 20;17(11):778–782. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2014.11.02

1.

17-DAMG在不同浓度和时间对细胞株的增殖抑制作用

The inhibitory effect of 17-DMAG on proliferation of cell lines treated by different concentrations and time

Cell lines	17-DMAG (μmol/L)	Inhibitory rate (%)			P
Cell lines	17-DMAG (μmol/L)	24 h	48 h	72 h	P
^: P value in groups of different concentrations.^*: P value in groups of different time.
A549	0.003	10.51±1.65	21.89±1.57	29.15±1.19	＜0.001^**
	0.03	17.60±1.43	28.76±3.06	38.64±2.31	＜0.001^**
	0.3	32.32±2.72	38.45±1.74	60.23±1.26	＜0.001^**
	3	42.58±3.31	57.38±1.21	78.45±1.34	＜0.001^**
	30	54.49±0.95	73.73±2.42	88.90±0.89	＜0.001^**
	P	＜0.001^*	＜0.001^*	＜0.001^*
H1975	0.003	8.75±2.43	16.43±2.63	28.81±3.06	＜0.001^**
	0.03	13.50±1.54	28.22±2.19	39.68±1.05	＜0.001^**
	0.3	22.71±3.54	40.30±5.23	56.26±2.50	＜0.001^**
	3	45.21±3.84	59.82±2.05	75.33±3.08	＜0.001^**
	30	70.51±2.41	81.17±5.38	90.61±2.51	0.002^**
	P	＜0.001^*	＜0.001^*	＜0.001^*