2.

NSCLC患者凝血指标与其临床病理特征的关系

Results (median) of comparisons between the coagulation tests and various clinical and pathological characteristic

Parameters	Coagulation tests
	PT (s)	PTA (%)	INR	APTT (s)	FIB (g/L)	D-dimer (mg/L)	PLT(×109/L)
Gender
Male	11.4	98	1.04	32.5	4.27	0.2	260
Female	11.0	99	1.02	31.1	3.93	0.3	287
P	0.007	0.002, 5	0.013, 5	＜0.001	＜0.001	0.499	0.816
Age (yr)
＜65	11.1	99	1.03	32.3	4.21	0.2	282
≥65	11.5	98	1.06	31.9	4.22	0.2	251
P	0.183	0.197	0.178	0.392	0.066	0.420	0.099
Histological type
Adenocarcinoma	11.8	93	1.08	31.5	4.11	0.2	279
Squamous cell carcinoma	11.0	101	1.01	32.7	4.70	0.3	258
P	0.006, 5	0.002, 5	0.008, 5	0.176	＜0.001	0.281	0.032
TNM stage
Ⅰ+Ⅱ	11.4	101	1.05	38.3	3.98	0.2	270
Ⅲ+Ⅳ	11.2	98	1.04	31.5	4.22	0.2	286
P	0.349	0.358	0.103	＜0.001	＜0.001	0.474	0.014
Lymphonode metastasis
N0	11.0	101	1.02	32.7	3.85	0.1	258
N1-N3	11.4	96	1.04	31.8	4.27	0.3	277
P	0.124	0.065	0.295	＜0.001	＜0.001	0.048	0.08