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. 2014 Aug 20;17(8):612–617. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2014.08.06

2.

IL-6-634和IL-1β-31位点多态性与非吸烟女性肺癌危险性的关系

Association between IL-6-634 and IL-1β-31 polymorphisms and the risk of lung cancer risk in female non-smokers

Genotypes Cases (%) Controls (%) OR (95%CI)a P value
a:OR; *:Statistically significant; OR:odds ratio; CI:confidence interval.
IL-6-634
  CC 193 (53.2) 233 (63.0) 1.00 (ref)
  CG 156 (43.0) 117 (31.6) 1.61 (1.19-2.19) 0.002*
  GG 14 (3.9) 20 (5.4) 0.85 (0.42-1.72) 0.642
  CG/GG 170 (46.8) 137 (37.0) 1.48 (1.10-1.98) 0.010*
IL-1β-31
  CC 89 (24.5) 80 (21.6) 1.00 (ref)
  CT 194 (53.4) 199 (53.8) 0.88 (0.61-1.26) 0.473
  TT 80 (22.0) 91 (24.6) 0.79 (0.52-1.21) 0.279
  CT/TT 274 (75.5) 290 (78.4) 0.85(0.60-1.20) 0.352