2.
IL-6-634和IL-1β-31位点多态性与非吸烟女性肺癌危险性的关系
Association between IL-6-634 and IL-1β-31 polymorphisms and the risk of lung cancer risk in female non-smokers
| Genotypes | Cases (%) | Controls (%) | OR (95%CI)a | P value |
| a:OR; *:Statistically significant; OR:odds ratio; CI:confidence interval. | ||||
| IL-6-634 | ||||
| CC | 193 (53.2) | 233 (63.0) | 1.00 (ref) | |
| CG | 156 (43.0) | 117 (31.6) | 1.61 (1.19-2.19) | 0.002* |
| GG | 14 (3.9) | 20 (5.4) | 0.85 (0.42-1.72) | 0.642 |
| CG/GG | 170 (46.8) | 137 (37.0) | 1.48 (1.10-1.98) | 0.010* |
| IL-1β-31 | ||||
| CC | 89 (24.5) | 80 (21.6) | 1.00 (ref) | |
| CT | 194 (53.4) | 199 (53.8) | 0.88 (0.61-1.26) | 0.473 |
| TT | 80 (22.0) | 91 (24.6) | 0.79 (0.52-1.21) | 0.279 |
| CT/TT | 274 (75.5) | 290 (78.4) | 0.85(0.60-1.20) | 0.352 |