1.
动物实验基本情况
Basic information about the experiment
| Group | Dose (mg/kg) | Number of mice | Frequency position | MW (Mean±SD, g) | TW (Mean±SD, g) |
T/C (%) | TIR | P # | ||
| B | E | B | E | |||||||
| NS: sterile normal saline; Biw: bis in week; #compared with control group; Perit: Peritumoral injection; CG: control group; EG: endostatin group; BG: bevacizumab group; COG: combining group; MW: mice weight; TW: tumor weight; B: before treatment; E: end of experiments; TIR: tumor inhibition rate; T/C (%) proliferation rate. | ||||||||||
| CG | N.S. | 6 | 6 | Perit×16 qd | 5.2±1.1 | 25.7±1.1 | 0.35±0.06 | |||
| EG | 3 | 6 | 6 | Perit×16 qd | 25.3±1.2 | 25.8±1.1 | 0.22±0.10 | 64.83 | 38.68 | < 0.01 |
| BG | 5 | 6 | 6 | Perit×6 Biw | 25.4±1.4 | 26.0±0.8 | 0.17±0.07 | 50.74 | 52.36 | < 0.01 |
| COG | 3 | 6 | 6 | Perit×16 qd | 24.4±1.2 | 25.6±0.4 | 0.13±0.07 | 41.30 | 64.15 | < 0.01 |
| 5 | Perit×6 Biw | |||||||||