3.
EGFR-TKIs治疗肺癌脑转移的在研试验
Ongoing trials of EGFR-TKIs therapy in NSCLC patients with brain metastases
| ClinicalTrials.gov identifier | Design | Intervention | EGFR mutation |
| NSCLC: non-small cell lung cancer. | |||
| NCT01887795 | Prospective randomized phase Ⅲ | WBRT vs WBRT+erlotinib | Unselected |
| NCT01724801 | Prospective randomized phase Ⅲ | WBRT vs icotinib | EGFR mutation |
| NCT01578668 | Prospective single arm phase Ⅱ | Erlotinib+chemotherapy (pemetrexed plus carboplatin) | Adenocarcinoma |
| NCT01218529 | Prospective single arm phase Ⅱ | WBRT+lapatinib | Unselected |