2.
Toppgene筛选新的肺腺癌疾病候选基因(注:选取P < 0.01的基因)
The screen of lung adenocarcinoma candidate genes using Toppgene (Note: Genes were selected based on P < 0.01)
| Rank | Gene Symbol | Gene ID | Average score | P |
| 1 | CD36 | 948 | 0.470 761 5 | 0.000 000 1 |
| 2 | HBEGF | 1839 | 0.529 077 5 | 0.000 000 6 |
| 3 | PMAIP1 | 5366 | 0.572 612 2 | 0.000 001 1 |
| 4 | TYMS | 7298 | 0.485 545 3 | 0.000 001 8 |
| 5 | TEK | 7010 | 0.486 797 7 | 0.000 001 8 |
| 6 | COL1A1 | 1277 | 0.319 382 1 | 0.000 004 |
| 7 | IGFBP3 | 3486 | 0.456 963 2 | 0.000 006 9 |
| 8 | SPP1 | 6696 | 0.503 422 5 | 0.000 007 |
| 9 | EDN1 | 1906 | 0.471 195 9 | 0.000 008 1 |
| 10 | TIE1 | 7075 | 0.541 537 4 | 0.000 010 4 |
| 11 | TGFBR3 | 7049 | 0.497 567 5 | 0.000 010 4 |
| 12 | CDKN1C | 1028 | 0.431 009 4 | 0.000 013 1 |
| 13 | NR4A1 | 3164 | 0.401 529 2 | 0.000 017 5 |
| 14 | CXCL2 | 2920 | 0.455 321 7 | 0.000 030 6 |
| 15 | BMP2 | 650 | 0.380 468 4 | 0.000 039 1 |
| 16 | CSF3 | 1440 | 0.438 977 1 | 0.000 200 2 |
| 17 | SFN | 2810 | 0.455 187 2 | 0.000 266 3 |
| 18 | MMP7 | 4316 | 0.398 214 1 | 0.000 267 |
| 19 | COL1A2 | 1278 | 0.362 644 5 | 0.000 572 2 |
| 20 | FABP4 | 2167 | 0.330 210 4 | 0.000 708 5 |
| 21 | CEACAM1 | 634 | 0.404 989 1 | 0.000 729 4 |
| 22 | LEPR | 3953 | 0.370 081 7 | 0.001 032 8 |
| 23 | DST | 667 | 0.388 865 5 | 0.001 492 4 |
| 24 | UBE2C | 11065 | 0.345 610 4 | 0.001 553 9 |
| 25 | GATA6 | 2627 | 0.280 920 4 | 0.001 912 6 |
| 26 | ATF3 | 467 | 0.307 962 8 | 0.002 073 1 |
| 27 | SORBS1 | 10580 | 0.395 258 5 | 0.002 167 8 |
| 28 | CXCL3 | 2921 | 0.384 477 2 | 0.002 625 5 |
| 29 | CRYAB | 1410 | 0.352 635 4 | 0.002 788 1 |
| 30 | EDNRB | 1910 | 0.334 035 3 | 0.003 291 3 |
| 31 | DLC1 | 10395 | 0.407 277 2 | 0.003 520 2 |
| 32 | HBB | 3043 | 0.283 212 9 | 0.004 263 6 |
| 33 | CP | 1356 | 0.349 502 5 | 0.004 849 8 |
| 34 | COL3A1 | 1281 | 0.291 960 6 | 0.006 152 1 |
| 35 | SLC2A1 | 6513 | 0.263 899 8 | 0.006 28 |
| 36 | NME1 | 4830 | 0.338 435 6 | 0.010 138 1 |