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晚期NSCLC患者ERCC1 C8092A、118多态性与含铂化疗疗效的关系
Genotype frequencies in patients with advanced NSCLC and response to cisplatin-based chemotherapy according to genotype
| Genotype | No. of patients (n/%) | χ2 | P | ||
| Frequencies | CR+PR | SD+PD | |||
| CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease. | |||||
| C8092A | 0.14 | 0.71 | |||
| CC | 36 (40.0) | 12 (33.3) | 24 (66.7) | ||
| CA+AA | 54 (60.0) | 16 (29.6) | 38 (70.4) | ||
| 118 | 0.64 | 0.43 | |||
| CC | 53 (58.9) | 17 (32.1) | 36 (67.9) | ||
| CT+TT | 37 (41.1) | 9 (24.3) | 28 (75.7) | ||