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晚期NSCLC患者ERCC1 C8092A、118多态联合与含铂化疗疗效的关系
Genotype frequencies in patients with advanced NSCLC and response to cisplatin-based chemotherapy according to combination of genotype in C8092A and 118
| C8092A | 118 | No. of patients (n/%) | P | ||
| n | CR+PR | SD+PD | |||
| *Fisher’ Exact Test. | |||||
| CC | CC | 15 (16.7) | 7 (46.7) | 8 (53.3) | |
| CC | CT+TT | 21 (23.3) | 3 (14.3) | 18 (85.7) | |
| CA+AA | CC | 38 (42.2) | 10 (26.3) | 28 (73.7) | |
| CA+AA | CT+TT | 16 (17.8) | 6 (37.5) | 10 (62.5) | 0.12* |
