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. 2014 May 20;17(5):391–400. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2014.05.05

1.

114例Ⅲb/Ⅳ期复治非小细胞肺癌(non-small cell lung cancer, NSCLC)患者的临床特征

The clinical characteristics of 114 patients with stage Ⅲb/Ⅳ lung cancer failed to chemotherapy chemotherapy

Variable n (114) propotion (%)
EGFR: epidermal growth factor receptor; CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease.
Gender
  Female 37 32.5
  Male 77 67.5
Median age at diagnosis
   < 65 year 91 79.8
  ≥65 year 23 20.2
Smoking characteristics
  Never smoker 58 50.9
  Current or former smoker 56 49.1
Performance status
  0-1 83 72.8
  2-3 31 27.2
Histology
  Adenocarcinoma 69 60.5
  Non-adenocarcinoma 45 39.5
EGFR status
  Mutation 23 20.2
  Wild 13 11.4
  Unknown 78 68.4
Staging before erlotinib treatment
  Ⅲb 10 8.8
  Ⅳ 104 91.2
Prior chemotherapy effect
  CR/PR/SD 99 86.8
  PD 15 13.2
Prior chemotherapy
  One regimen 64 56.1
  Two or more regimens 50 43.9