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114例Ⅲb/Ⅳ期复治非小细胞肺癌(non-small cell lung cancer, NSCLC)患者的临床特征
The clinical characteristics of 114 patients with stage Ⅲb/Ⅳ lung cancer failed to chemotherapy chemotherapy
| Variable | n (114) | propotion (%) |
| EGFR: epidermal growth factor receptor; CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease. | ||
| Gender | ||
| Female | 37 | 32.5 |
| Male | 77 | 67.5 |
| Median age at diagnosis | ||
| < 65 year | 91 | 79.8 |
| ≥65 year | 23 | 20.2 |
| Smoking characteristics | ||
| Never smoker | 58 | 50.9 |
| Current or former smoker | 56 | 49.1 |
| Performance status | ||
| 0-1 | 83 | 72.8 |
| 2-3 | 31 | 27.2 |
| Histology | ||
| Adenocarcinoma | 69 | 60.5 |
| Non-adenocarcinoma | 45 | 39.5 |
| EGFR status | ||
| Mutation | 23 | 20.2 |
| Wild | 13 | 11.4 |
| Unknown | 78 | 68.4 |
| Staging before erlotinib treatment | ||
| Ⅲb | 10 | 8.8 |
| Ⅳ | 104 | 91.2 |
| Prior chemotherapy effect | ||
| CR/PR/SD | 99 | 86.8 |
| PD | 15 | 13.2 |
| Prior chemotherapy | ||
| One regimen | 64 | 56.1 |
| Two or more regimens | 50 | 43.9 |