2.

c-Jun、NFAT3表达与非小细胞肺癌患者临床病理因素之间的关系

Association between expression of c-Jun and NFAT3 and clinicopathologic characteristics of non-small cell lung cancer

Clinicopathologic characteristics (n=159)	n	Expression of c-Jun		X2	P	Expression of NFAT3		X2	P
		Positive	Rate			Positive	Rate
Age				3.595	0.058			0.004	0.951
≤60	63	5	7.9%			18	28.6%
> 60	96	18	18.8%			27	28.2%
Gender				0.911	0.340			1.890	0.169
Male	111	18	16.2%			35	31.5%
Female	48	5	10.4%			10	20.8%
Smoking status				1.511	0.219			1.196	0.158
Never	67	7	10.2%			15	22.3%
Smoker	92	16	17.4%			30	32.6%
Differentiation				2.523	0.283			3.326	0.190
High	8	2	25.0 %			2	25.0%
Moderate	103	17	16.5%			34	33.0%
Low	48	4	8.3%			9	18.8%
Histologic type				2.804	0.094			0.470	0.493
Adenocarcinoma	74	7	9.5%			19	25.7%
Squamous cell carcinoma	85	16	18.8%			26	30.6%
Lymph node metastasis				0.425	0.515			0.014	0.904
No	73	12	39.5%			21	28.8%
Yes	86	11	46.6%			24	27.9%
TNM staging				0.736	0.391			1.167	0.280
Ⅰ + Ⅱ	109	14	12.8%			28	25.7%
Ⅲ	50	9	18.0%			17	34.0%