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ERCC1和GST-pi的表达与肺癌患者临床病理特征的关系

The relationship between ERCC1 expression, GST-pi expression and clinical pathophysicological characteristics of lung cancer patients

Characteristics	ERCC1 expression						GST-pi expression
	Cases	Positive	Positive rate (%)	χ2	P		Cases	Positive	Positive rate (%)	χ2	P
Age (year)				2.992	0.084					1.195	0.274
< 65	36	18	50.0				36	24	66.7
>65	112	38	33.9				112	8S	75.9
Sex				0.251	0.616					1.122	0.290
Male	104	38	36.5				104	74	71.2
Female	44	18	40.9				44	35	79.5
Smoking status				2.159	0.142					4.499	0.034
Non-smokers	55	25	45.5				55	46	83.6
Smokers	93	31	33.3				93	63	67.7
Cigarette smoking index				3.867	0.049					1.469	0.226
< 400	88	39	44.3				88	68	77.3
>400	60	17	28.3				60	41	68.3
Histology				4.245	0.039					23.299	<0.001
Small cell lung cancer	22	4	18.2				22	7	31.8
Non-small cell lung cancer 26		52	41.3	0.703	0.402		126	102	81.0	0.505	0.477
Squamous carcinoma	50	19	38.0				50	42	84.0
Adenocarcinoma	61	28	45.9				61	48	78.7
Differentiation grade				5.832	0.016					3.247	0.072
Pooriy and undifferentiated 69		19	27.5				69	46	66.7
Moderately and highly	79	37	46.8				79	63	79.7
Size of the tumor				2.451	0.117					0.569	0.451
T1+T2	111	46	41.4				111	80	72.1
T3+T4	37	10	27.0				37	29	78.4
Lymphatic metastasis				0.297	0.586					0.180	0.671
Positive	65	23	35.4				65	49	7S.4
Negative	83	33	39.8				83	60	72.3
TNM stage				0.569	0.451					1.166	0.280
Ⅰ+Ⅱ	111	80	72.1				83	64	77.1
Ⅲ	37	29	78.4				65	45	69.2