2.

肺癌组织中IL-8、MMP-9免疫组化表达水平与临床病理特征的关系

The relationship between tissue IL-8 and MMP-9 expressions and the clinicopathological characteristics

Variables	n	IL-8 status		P	MMP-9 status		P
		Positive	Negative		Positive	Negative
Group				< 0.001			< 0.001
Normal lung tissue	25	2	23		3	22
Benign lung tissue	21	4	17		6	15
Lung cancer tissue	95	60	35		62	33
Pathologic stage				0.002			0.022
Stage Ⅰ	38	18	20		20	18
Stage Ⅱ	19	10	9		11	8
Stage Ⅲ, Ⅳ	38	32	6		31	7
Tumor status				0.504			0.071
T1	17	9	8		7	10
T2	54	24	20		38	16
T3, T4	24	17	7		17	7
Lymph node status				0.008			0.022
N0	51	26	25		28	23
N1, N2, N3	44	34	10		34	10
Distant metastasis				0.082			0.089
Present	89	54	35		56	33
Absent	6	6	0		6	0
Tumor size				0.513			0.325
< 3 cm	34	20	14		20	14
> 3 cm	61	40	21		42	19
Histology				0.206			0.730
Adenocarcinoma	50	34	16		33	17
Squamous cell carcinoma	40	22	18		25	15
Differentiation				0.721			0.061
Poorly	9	5	4		3	6
Moderately, Well	86	55	31		59	27
Location				0.251			0.413
Central	37	26	11		26	11
Peripheral	58	34	24		36	22
Gender				0.530			0.748
Male	79	51	28		51	28
Female	16	9	7		11	5
Age (years)				0.606			0.064
< 60	44	29	15		33	11
> 60	51	31	20		29	22
Smoking				0.385			0.429
Non-smoker	38	22	16		23	15
Smoker	57	38	19		39	18