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. 2018 May 11;33(25):e171. doi: 10.3346/jkms.2018.33.e171

Table 4. Changes of echocardiographic parameters, log NT-proBNP, and GAS after 6-month treatment of bisoprolol.

Echocardiography Baseline 6 mon Change P value
Baseline vs. 6 mon Low HR vs. high HR
LVEDD, mm 0.035
Low HR 64 ± 6 61 ± 8 3 ± 5 0.001
High HR 64 ± 8 58 ± 10 6 ± 8 < 0.001
LVESD, mm 0.207
Low HR 51 ± 13 45 ± 15 7 ± 15 0.003
High HR 54 ± 11 45 ± 12 9 ± 13 < 0.001
LVEF, % 0.023
Low HR 28 ± 7 38 ± 12 10 ± 10 < 0.001
High HR 28 ± 7 42 ± 12 14 ± 12 < 0.001
LVRR, No. (%) 0.008
Low HR 7 (15.6)
High HR 42 (37.5)
Log NT-proBNP, pg/mL 0.122
Low HR 2.9 ± 0.5 2.7 ± 0.6 0.2 ± 0.5 0.051
High HR 2.9 ± 0.6 2.6 ± 0.6 0.3 ± 0.5 < 0.001

NT-proBNP = N-terminal pro b-type natriuretic peptide, GAS = global assessment score, HR = heart rate, LVEDD = left ventricular end-diastolic dimension, LVESD = left ventricular end-systolic dimension, LVEF = left ventricular ejection fraction, LVRR = left ventricular reverse remodeling.