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IL-7和IL-7R蛋白表达与NSCLC患者临床因素之间的关系
Relationship between IL-7 and IL-7R expression in NSCLC and clinical pathological factors
| Factors | n | IL-7 expression [n (%)] | P | IL-7R expression [n (%)] | P |
| *P < 0.05; NSCLC: non-small cell lung cancer; IL-7: interleukin-7; IL-7R: interleukin-7 receptor. | |||||
| Gender | 0.571 | 0.752 | |||
| Male | 71 | 46(64.79%) | 44(61.97%) | ||
| Female | 24 | 14(58.33%) | 14(58.33%) | ||
| Age (years) | 0.356 | 0.169 | |||
| ≤60 | 52 | 35(67.31%) | 35(67.31%) | ||
| > 60 | 43 | 25(58.14%) | 23(53.49%) | ||
| Histology | 0.664 | 0.606 | |||
| Squamous cance | 57 | 35(61.40%) | 36(63.16%) | ||
| Adenocarcinoma | 38 | 25(65.79%) | 22(57.89%) | ||
| Differentiation | 0.255 | 0.439 | |||
| Well & Moderate | 56 | 38(67.86%) | 36(64.29%) | ||
| Poor | 39 | 22(56.41%) | 22(56.41%) | ||
| Lymph node metas | < 0.001* | < 0.001* | |||
| Positive | 58 | 45(77.59%) | 44(75.86%) | ||
| Negative | 37 | 15(40.54%) | 14(37.84%) | ||
| Distant metastasis | 0.188 | 0.326 | |||
| Positive | 47 | 31(65.96%) | 32(68.09%) | ||
| Negative | 48 | 23(47.92%) | 26(54.17%) | ||
| Stage | 0.001* | 0.005* | |||
| Ⅰ-Ⅱ | 42 | 19(42.86%) | 19(42.86%) | ||
| Ⅲ-Ⅳ | 53 | 41(77.36%) | 39(73.58%) | ||