1.

肺癌患者化疗前后不同时期EORTC-C30各领域得分比较（Mean±SD）

Compare of the scores for EORTC QLQ-C30 in different periods of chemotherapy (Mean±SD)

	Baseline	After 2 cycles	After 4 cycles	F	P
If the scores are normal distribution, they are expressed as Mean±SD, and use analysis of variance, SNK comparative method; if the scores are not normal distribution, they are expressed as median, and use Kruskal-Wallis rank sum test; *Compare with before chemotherapy and after 2 cycles, P < 0.05；△Compare with after 2 cycles and after 4 cycles, P < 0.05; ※Compare with before chemotherapy and after 4 cycles, P < 0.05.
Physical	79.964±11.145	74.390±10.320	67.809±14.812△※	5.477	0.005
Role	65.064±23.637	61.858±19.064	51.921±20.270△※	5.495	0.005
Emotional	63.603±25.890	62.173±20.717	49.648±18.230△※	6.420	0.002
Cognitive	64.721±28.890	67.931±21.592	67.623±18.201	0.299	0.742
Social	63.131±23.432	55.452±77.391*	42.622±12.553△※	16.611	0.000
Fatigue	49.731±25.152	48.543±21.901	54.722±20.042	1.107	0.333
Pain	25.642±24.790	30.772±21.990	37.182±23.241※	3.184	0.044
Nause and vomiting	20.832±20.012	29.704±20.841*	37.513±20.051△※	8.459	0.000
Dyspnoea	49.351±33.990	37.163±25.281	41.022±24.371	2.535	0.083
Insomnia	32.042±31.641	45.512±26.441*	46.153±24.851※	4.270	0.160
Appetite loss	33.974±30.610	46.793±28.221*	64.754±27.561△※	14.96	0.000
Constipation	28.204±20.141	31.413±30.551	43.594±32.701	2.972	0.054
Diarrhea	28.843±27.101	29.493±29.271	28.843±27.041	0.008	0.992
Financial impact	38.464±32.613	41.664±32.931	55.134±36.091△※	3.537	0.032
Global quality of life	58.637±22.761	53.194±15.598	45.810±14.351△※	6.693	0.002