5.
BIM基因多态性与毒副作用的关系分析
Analysis of the relationship between BIM gene polymorphism and side effects
| Toxic reaction | Ⅰ-Ⅳ degree (n) | χ2 | P | Ⅲ-Ⅳ degree (n) | χ2 | P | ||
| No polymorphism | Polymorphism | No polymorphism | Polymorphism | |||||
| Rash | 62 | 12 | 0.096 | 0.756 | 10 | 2 | 0.133 | 0.716 |
| Diarrhea | 34 | 5 | 0.730 | 0.393 | 9 | 1 | 0.033 | 0.856 |
| Feeble | 18 | 3 | 0.003 | 0.957 | 5 | 1 | 0.280 | 0.597 |
| Interstitial pneumonia | 3 | 0 | 0.000 | 0.985 | 1 | 0 | 0.208 | 0.249 |
| Liver function damage | 5 | 1 | 0.280 | 0.597 | 1 | 0 | 0.208 | 0.249 |