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. 2013 Dec 20;16(12):632–638. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2013.12.03

5.

BIM基因多态性与毒副作用的关系分析

Analysis of the relationship between BIM gene polymorphism and side effects

Toxic reaction Ⅰ-Ⅳ degree (n) χ2 P Ⅲ-Ⅳ degree (n) χ2 P
No polymorphism Polymorphism No polymorphism Polymorphism
Rash 62 12 0.096 0.756 10 2 0.133 0.716
Diarrhea 34 5 0.730 0.393 9 1 0.033 0.856
Feeble 18 3 0.003 0.957 5 1 0.280 0.597
Interstitial pneumonia 3 0 0.000 0.985 1 0 0.208 0.249
Liver function damage 5 1 0.280 0.597 1 0 0.208 0.249