2.

E-cadherin基因甲基化与肺癌易感性

Summary of E-cadherin methylation and lung cancer risk

Variables	No.a	Cases/Controls	OR (95%CI)	PHb	I2 (%)
aNo. of studies; bP value of Q test for heterogeneity.
Total	13	692/596	4.04 (2.00-8.13)	< 0.001	74.9
Ethnicities
Asian	7	378/342	3.28 (1.20-8.92)	< 0.001	77.9
Caucasion	3	163/142	5.72 (2.40-13.62)	0.056	65.4
Mixed	3	151/112	4.77 (0.96-23.70)	0.001	86.5
Testing materials
Tissue	12	672/586	4.00 (1.94-8.24)	< 0.001	77.0
Blood	1	20/10	5.73 (0.28-117.65)	-	-
Testing methods
MSP	9	504/480	4.40 (2.28-8.48)	0.023	54.9
Others	4	188/116	2.69 (0.41-17.69)	< 0.001	89.9