3.

两组患者治疗不良反应的比较

Comparison of the toxicity of treatments in the two groups

Adverse event (G1-4/G3-4)	Pemetrexed (n=23)	Gefitinib (n=23)
Compared with Gefitinib, Δχ2=5.8545, P < 0.05; □χ2=6.0919, P < 0.05; Compared with Pemetrexed, ☆χ2=4.3810, P < 0.05; ※χ2=6.0919, P < 0.05.
Hematologic toxicity
Anemia	4/0	1/0
Neutropenia	9Δ/1	2/0
Thrombocytopenia	2/0	0/0
Non-hematologic toxicity
Fatigue	8□/1	1/0
Anorexia	5/1	2/0
Nausea/vomiting	3/0	2/0
Constipation	2/0	0/0
Diarrhea	0/0	4☆/1
Stomatitis	1/0	1/1
Skin disorders	1/0	8※/2
Elevated transaminas	4/0	2/0
Fever	3/0	0/0