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VEGF基因中SNP位点与肺癌易感性、疗效预测和预后之间关系

The relationship between VEGF SNPs and the risk of lung cancer, predictive value to therapy and prognosis

SNP site	Risk of lung cancer	Predictive value	Prognosis
The sign "↑" stands for increasing risk to getting lung caner, while, "↓" means decreasing the risk. In the column of predictive value, compare the response rate of chemotherapy between different genotypes. The comparison of overall survival (OS) are shown in prognosis column. Such as -1154G > A, GG vs AA+AG, it means that the patients OS with GG are better than those with AA and AG.
-2578C > A	CA vs CC+AA[16]↓
-1154G > A		GG > AG > AA[22]	GG vs AA+AG[22]
-460T > C	TT vs CC[18]↑		CC+CT vs TT[30]
	TT vs CC+CT[18]↑
-634G > C	CC+CG vs GG[14]↑		CC+CG vs GG[29]
	CG vs GG; GG vs CC [16]↓
	CC+CG vs GG[15]↓
+936C > T	CT+TT vs CC[15, 16]↓		CC+CT vs TT[29]