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Refolding of luciferase. Refolding of luciferase in rabbit reticulocyte lysate is compromised in the presence of (A) LA1011 and (B) geldanamycin. Red, control without LA1011, or geldanamycin, blue, 1 mM LA1011, or 2 μM geldanamycin and black 5 mM LA1011 or 5 μM geldanamycin. Errors bars represent standard error and the experiment was carried out in triplicate.
