1.

患者临床特征与疗效

The characteristics of the patients and the efcacy

Characteristics		n	RR (n)	χ2	P	DCR(n)	χ2	P
*: Fisher exact test. RR: response rate; DCR: disease control rate.
Gender	Male	28	9	0.003	0.960	17	1.351	0.245
	Female	49	17			36
Age	≥65	35	12	0.008	0.930	21	2.333	0.127
	< 65	42	14			32
PS score	0-1	51	18	0.158	0.691	40	6.489	0.011
	2-3	26	8			13
Histology	Adenocarcinoma	60	26	11.122	0.001	47	11.438	0.001
	Others	17	0			6
Stage	Ⅲb	22	11	3.629	0.057	18	2.421	0.120
	Ⅳ	55	15			35
Smoker	Yes	23	41	3.932	0.047	11	6.745	0.009
	No	54	22			42
Skin rash	Yes	43	23	16.937	0.000	38	17.333	0.000
	No	34	3			15
EGFR mutation	Yes	3	3	-	0.028*	3	-	0.209*
	No	11	2			5
	Unkown	63	-	-	-	-	-	-
Serum CEA	Decline	28	20	28.536	0.000	27	22.818	0.000
	Unchanged	22	4			16
	Increase	27	2			10