1.

纳入文献的一般情况（斜体字为不符合HWE的研究，MAF：次要等位基因频率）

Characteristics of studies included in the meta-analysis (Italic type indicates the distribution of the genotypes in controls of the study is not in HWE. MAF: minor allele frequency)

First author (year)	Ethnicity	Country of research	Source of control	Genotyping	Lung cancer/Control	MAF of control
Hu (2006)[15]	Asian	China	Hospital	Taqman	970/986	A:0.057
Kong FJ (2006)[26]	Asian	China	Hospital	RFLP	120/120	A:0.058
Liang (2003)[11]	Asian	China	Population	RFLP	1 006/1 020	A:0.065
Shen (2005)[16]	Asian	USA	Population	Real-time PCR	118/113	A:0.062
Yin (2008)[17]	Asian	China	Hospital	RFLP	201/171	A:0.006
Butkiewicz (2001)[10]	Caucasian	Poland	Population	RFLP	96/94	A:0.436
De Ruyck (2007)[18]	Caucasian	Belgium	Hospital	RFLP	110/109	A:0.339
Hou (2002)[9]	Caucasian	Sweden	Population	RFLP	184/162	A:0.370
Lopez-Cima (2007)[19]	Caucasian	Spain	Hospital	RFLP	516/533	A:0.296
Matullo (2006)[20]	Caucasian	Italy	Population	Taqman	116/1 094	A:0.387
Misra (2003)[12]	Caucasian	Finland	Population	Taqman	313/312	A:0.364
Popanda (2004)[21]	Caucasian	Germany	Hospital	RFLP	463/460	A:0.370
Raaschou (2008)[22]	Caucasian	Denmark	Population	Real-time PCR	424/787	A:0.359
Zhou (2002)[24]	Caucasian	USA	Population	RFLP	1 092/1 240	A:0.331
Zienolddiny (2006)[23]	Caucasian	Norwegian	Population	Taqman	275/290	A:0.378
Chang (2008)[25]	African-American	USA	Population	GoldenGate	247/277	A:0.126
Chang (2008)[25]	Latinos	USA	Population	GoldenGate	108/297	A:0.197
Spitz (2001)[7]	Mixed-ethnicity	USA	Population	RFLP	195/257	A:0.272