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. 2010 May 20;13(5):526–532. [Article in Chinese] doi: 10.3779/j.issn.1009-3419.2010.05.27

3.

不同遗传模型下XPD G312A位点的meta分析结果

Summary of OR with CI for various genetic contrasts of G312A polymorph and lung cancer risk (*the pooled analysis excluding the study that was not in HWE)

Ethnicity Studies Contrast
(Lung cancer/Control) A vs G AA vs AG+GG AG+AA vs GG AA vs GG
Phetero I2 P OR (95%CI) Phetero I2 P OR (95%CI) Phetero I2 P OR (95%CI) Phetero I2 P OR (95%CI)
Total 18(6554/8322) 0.71 0 0.05 1.06(1.00-1.12) 0.39 5 0.004 1.20(1.06-1.36) 0.62 0 0.43 1.03 (0.96-1.11) 0.37 7 0.01 1.19(1.04-1.36)
Total* 17(6353/8151) 0.69 0 0.05 1.06(1.00-1.12) 0.37 7 0.004 1.20 (1.06-1.36) 0.55 0 0.42 1.03 (0.96-1.11) 0.35 9 0.01 1.19(1.04-1.36)
Asian 5(2415/2410) 0.48 0 0.20 1.12(0.94-1.32) 0.30 18 0.007 4.43(1.51-12.99) 0.65 0 0.47 1.07 (0.89-1.28) 0.30 17 0.007 4.45(1.52-13.07)
Asian* 4(2214/2239) 0.41 0 0.18 1.12(0.95-1.33) 0.78 0 0.004 7.15(1.90-26.94) 0.49 0 0.46 1.07 (0.89-1.28) 0.79 0 0.004 7.20(1.91-27.15)
Caucasian 10(3589/5081) 0.69 0 0.24 1.04 (0.97-1.11) 0.66 0 0.040 1.15 (1.01-1.31) 0.40 5 0.87 1.01 (0.92-1.10) 0.68 0 0.09 1.13 (0.98-1.30)