4.
ENT3 rs10999776多态位点基因型联合吸烟与肺癌不同病理类型的关系
The relationship between the genotypes of rs10999776 combined with smoking and the pathologic types of lung cancer
| Genotypes | Smoking history (packs/year) | AC (n=192) | SCC (n=100) | Control (n=207) | OR (95%CI)a | Pa | OR (95%CI)b | Pb |
| a: The comparison of the groups of lung adenocarcinoma (AC) and control; b: The comparison of the groups of lung squamous cell carcinoma (SCC) and control. | ||||||||
| CC | Non-smokers | 58 | 13 | 60 | 1.000 | 1.000 | ||
| Smokers | 46 | 34 | 61 | 0.780 (0.461-1.320) | 0.355 | 2.573 (1.238-5.348) | 0.010 | |
| < 30 | 18 | 6 | 32 | 0.582 (0.295-1.150) | 0.117 | 0.865 (0.300-2.493) | 0.789 | |
| > 30 | 28 | 28 | 29 | 0.999 (0.530-1.880) | 0.997 | 4.456 (2.016-9.850) | 0.000 | |
| TC+TT | Non-smokers | 51 | 7 | 51 | 1.034 (0.609-1.758) | 0.900 | 0.633 (0.235-1.708) | 0.364 |
| Smokers | 37 | 46 | 35 | 1.094 (0.608-1.966) | 0.765 | 6.066 (2.884-12.758) | < 0.001 | |
| < 30 | 16 | 11 | 15 | 1.103 (0.500-2.435) | 0.807 | 3.385 (1.267-9.039) | 0.012 | |
| > 30 | 21 | 35 | 20 | 1.086 (0.534-2.211) | 0.820 | 8.077 (3.581-18.215) | < 0.001 | |