Figure 2. Effect of PD98059 (ERK inhibitor) on cell viability and NF-ĸB activation in SK-Hep1 cells. Cells were treated with different concentrations (0-30 μM in 0.1% DMSO) of PD98059 for 48 h. (A) Change of cell viability was evaluated by using MTT assay, (B) NF-ĸB activation was investigated with NF-ĸB reporter gene assay and corrected by using cell viability. *p<0.05 and **p<0.01 compared to control (0.1 % DMSO treatment).
