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Cholinergic lesions in the mPFC have no effect on fear or extinction memory. A) Infusion of 192-IgG saporin into the mPFC attenauted AChE fiber expression in the ACC and IL, but not PL. B) This treatment also had no effect on ChAT positive cell counts in the MS/vDBB. C) mPFC cholinergic lesions had no effect on conditioned freezing during fear conditioning, extinction training, or extinction testing.
