Table 2.
Polymorphism frequencies among the study participants.
| SNPs | Controls | RA patients | OR (95% CI) | AOR (95% CI) |
|---|---|---|---|---|
| (N=371) | (N=217) | |||
| rs10491121 | ||||
| A/A | 94 (25.3%) | 54 (24.9%) | 1.00 | 1.00 |
| A/G | 175 (47.2%) | 105 (48.4%) | 1.04 (0.69-1.58) | 0.82 (0.53-1.28) |
| G/G | 102 (27.5%) | 58 (26.7%) | 0.99 (0.62-1.58) | 0.91 (0.56-1.49) |
| A/G+G/G | 277 (77.7%) | 163 (75.1%) | 1.02 (0.70-1.51) | 0.85 (0.56-1.27) |
| rs1719153 | ||||
| A/A | 162 (43.7%) | 80 (36.9%) | 1.00 | 1.00 |
| A/T | 164 (44.2%) | 108 (49.8%) | 1.33 (0.93-1.91) | 0.67 (0.46-0.99)# |
| T/T | 45 (12.1%) | 29 (13.4%) | 1.31 (0.76-2.24) | 0.77 (0.44-1.35) |
| A/T+T/T | 209 (56.3%) | 137 (63.2%) | 1.33 (0.94-1.87) | 0.69 (0.48-0.99)# |
| rs1634507 | ||||
| C/C | 161 (43.4%) | 90 (41.5%) | 1.00 | 1.00 |
| A/C | 165 (44.5%) | 98 (45.2%) | 1.06 (0.74-1.52) | 0.81 (0.55-1.19) |
| A/A | 45 (12.1%) | 29 (13.4%) | 1.15 (0.68-1.97) | 0.89 (0.51-1.57) |
| A/C+A/A | 210 (56.6%) | 127 (58.6%) | 1.08 (0.77-1.52) | 0.83 (0.58-1.19) |
Data are represented as N (%).
# p< 0.05.
SNP: single nucleotide polymorphism; RA: rheumatoid arthritis; OR: odds ratio; CI: confidence interval; AOR: adjusted odds ratio.