Table 2.
Genotype distribution of the rs1544223 and its associations with the risk of chronic heart failure under different contrast models.
| Genotype | CHF n (%) |
Controls n (%) |
HWE Pa |
Dominant model Pa; Pb, OR (95% CI) |
Recessive model Pa; Pb, OR (95% CI) |
Additive model Pa; Pb, OR (95% CI) |
Allele contrast Pa; Pb, OR (95% CI) |
|---|---|---|---|---|---|---|---|
| rs1544223 | |||||||
| (Xi'an) | |||||||
| GG (W) | 30 (10.03) | 63 (15.83) | 0.0732 | 0.0259; 0.046, | 0.2415; 0.207, | 0.0764; 0.059, | 0.0471; 0.055, |
| AG | 131 (43.81) | 169 (42.46) | 1.662 | 1.233 | 1.256 | 1.265 | |
| AA | 138 (46.15) | 166 (41.71) | (1.009–2.738) | (0.890–1.708) | (0.991–1.593) | (0.995–1.608) | |
|
| |||||||
| rs1544223 | |||||||
| (Kunming) | |||||||
| GG | 25 (9.21) | 58 (14.43) | 0.0510 | 0.011; 0.048, | 0.017; 0.075, | 0.011; 0.025, | 0.002; 0.02, |
| AG | 116 (37.83) | 165 (41.04) | 1.689 | 1.338 | 1.31 | 1.336 | |
| AA | 163 (52.96) | 179 (44.53) | (1.004–2.841) | (0.971–1.843) | (1.034–1.661) | (1.046–1.706) | |
CHF: chronic heart failure; HWE: Hardy-Weinberg equilibrium; aP values were calculated from two-sided χ2-test. bAdjusted for age, sex, and cardiovascular risk factors (hypertension, dyslipidemia, diabetes, and smoking habit).