. 2018 May 31;2018:4969385. doi: 10.1155/2018/4969385

Table 3.

Rs1544223 polymorphism genotype distribution and allele frequency according to NYHA and subsets of CHF patients.

Genotype	NYHA			Hypertension	Dyslipidemia	Diabetes	Smoking habit
Genotype	II	III	IV	Hypertension	Dyslipidemia	Diabetes	Smoking habit
rs1544223 (Xi'an)
GG	12 (12.77%)	10 (8.55%)	8 (9.09%)	15 (8.77%)	8 (9.64%)	12 (11.54%)	10 (10.99%)
AG	43 (45.74%)	50 (42.74%)	38 (43.18%)	84 (49.12%)	32 (38.55%)	41 (39.42%)	41 (45.05%)
AA	39 (41.49%)	57 (48.72%)	42 (47.73%)	72 (42.11%)	43 (51.81%)	51 (49.04%)	40 (43.96%)
Allele frequency	0.4163^a			0.3982^b	0.3255^b	0.7916^b	0.5844^b
(P-value)	0.4163^a			0.3982^b	0.3255^b	0.7916^b	0.5844^b
Genotype distribution	0.7704^a			0.0991^b	0.4633^b	0.5095^b	0.8598^b
(P-value)	0.7704^a			0.0991^b	0.4633^b	0.5095^b	0.8598^b
rs1544223 (Kunming)
GG	5 (4.95%)	14 (11.86%)	6 (7.06%)	11 (6.47%)	4 (5.71%)	5 (4.95%)	5 (5.49%)
AG	36 (35.64%)	45 (38.14%)	35 (41.18%)	64 (37.65%)	24 (34.29%)	38 (37.62%)	37 (40.66%)
AA	60 (59.41%)	59 (50%)	44 (51.76%)	95 (55.88%)	42 (60%)	58 (57.43%)	49 (53.85%)
Allele frequency	0.1600^a			0.2105^b	0.1784^b	0.1669^b	0.5928^b
(P-value)	0.1600^a			0.2105^b	0.1784^b	0.1669^b	0.5928^b
Genotype distribution	0.3193^a			0.3992^b	0.4180^b	0.3026^b	0.4989^b
(P-value)	0.3193^a			0.3992^b	0.4180^b	0.3026^b	0.4989^b

NYHA: New York Heart Association class; ^aχ²-test -test: allele frequency and genotype distribution among the three groups; ^bχ²-test -test: allele frequency and genotype distribution versus controls.