Table 2.
Anxiety and depression score and severity by study arm
| Measure | Arm | Baseline | After RT | p-valuea | ||||
|---|---|---|---|---|---|---|---|---|
| n | mean ± std | median | n | mean ± std | median | |||
| Anxiety | Control | 144 | 5.03 ± 3.17 | 5.0 | 144 | 5.13 ± 3.15 | 5.0 | |
| Intervention | 135 | 5.29 ± 3.27 | 5.0 | 135 | 5.87 ± 3.18 | 6.0 | ||
| all | 279 | 5.15 ± 3.22 | 5.0 | 279 | 5.49 ± 3.18 | 5.0 | 0.02 | |
| Depression | Control | 145 | 4.57 ± 3.46 | 4.0 | 143 | 5.01 ± 3.65 | 5.0 | |
| Intervention | 136 | 5.02 ± 3.41 | 5.0 | 135 | 5.81 ± 3.68 | 5.0 | ||
| all | 281 | 4.79 ± 3.44 | 4.0 | 278 | 5.40 ± 3.68 | 5.0 | 0.00 | |
| normal | borderline | abnormal | normal | borderline | abnormal | |||
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |||
| Anxiety | Control | 113(77.9) | 25(17.2) | 6(4.1) | 112(77.2) | 25(17.2) | 7(4.8) | |
| Intervention | 109(80.2) | 17(12.5) | 9(6.6) | 100(73.5) | 23(16.9) | 12(8.8) | ||
| all | 222(79.0) | 42(15.0) | 15(5.3) | 212(75.4) | 48(17.1) | 19(6.8) | ns | |
| Depression | Control | 117(80.7) | 18(12.4) | 10(6.9) | 110(75.9) | 23(15.9) | 10(6.9) | |
| Intervention | 101(74.3) | 25(18.4) | 10(7.4) | 91(66.9) | 30(22.1) | 14(10.3) | ||
| all | 218(77.6) | 43(15.3) | 20(7.1) | 201(71.5) | 53(18.9) | 24(8.5) | ns | |
RT radiotherapy, std standard deviation, ns not significant at p > 0.20
ap value was from the simple Student’s t-test or proportions equal test in comparing the overall mean or ‘abnormal’ category percents before and after radiotherapy for anxiety and depression measures. Patients with missing score were treated as one category for percent calculation but not reported