Table 1.
Comparison of RNA-seq and qPCR data
| Ssc gene symbol | Ssc Entrez Gene ID | Hsa gene symbol | Hsa Entrez Gene ID | Hsa gene description | log2 FC P/C | P-value* | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RNA-seq | qPCR | RNA-seq | qPCR | ||||||||||||||
| LE | GE | S | Complete | D12 | D14 | LE | GE | S | Complete | D12 | D14 | PubMed ID | |||||
| ABCC1 | 733,619 | ABCC1 | 4363 | ATP binding cassette subfamily C member 1 | 3.5 | 1.4 | 1.1 | 2.4 | 1.6 | – | < 0.001 | 0.224 | 0.321 | < 0.001 | < 0.01 | – | 27764917 |
| LOC100738425 | 100,738,425 | ABCC4 | 10,257 | multidrug resistance-associated protein 4 | nd | 2.9 | nd | 2.2 | 2.1 | – | – | 0.019 | – | 0.001 | < 0.001 | – | 24695625 |
| ABCC9 | 100,127,449 | ABCC9 | 10,060 | ATP binding cassette subfamily C member 9 | 1.2 | 0.0 | 0.6 | 2.2 | 1.8 | – | < 0.001 | 0.999 | 0.844 | < 0.001 | < 0.05 | – | 27764917 |
| AKR1B1 | 396,816 | AKR1B1 | 231 | aldo-keto reductase family 1 member B | 5.2 | 5.2 | 2.2 | 5.1 | 5.8 | – | < 0.001 | < 0.001 | 0.060 | < 0.001 | < 0.001 | – | 24695626 |
| BAALC | 100,170,128 | BAALC | 79,870 | brain and acute leukemia, cytoplasmic | nd | nd | nd | −5.0 | −5.8 | – | – | – | – | < 0.001 | < 0.001 | – | 24174570 |
| LOC100157834 | 100,157,834 | CDH17 | 1015 | cadherin 17, LI cadherin (liver-intestine) | −6.5 | −2.6 | −5.8 | −8.3 | −6.3 | – | < 0.001 | 0.001 | < 0.001 | < 0.001 | < 0.001 | – | 24174570 |
| CLDN1 | 100,625,166 | CLDN1 | 9076 | claudin 1 | 5.0 | nd | 4.2 | 3.4 | 1.8 | – | < 0.001 | – | < 0.001 | < 0.001 | 0.002 | – | 25123632 |
| PBD-2 | 404,699 | DEFB1 | 1672 | defensin, beta 1 | −5.2 | −1.7 | −4.1 | −6.4 | −5.9 | −3.4 | < 0.001 | 0.015 | < 0.001 | < 0.001 | < 0.001 | 0.010 | 24174570 |
| FGF9 | 396,717 | FGF9 | 2254 | fibroblast growth factor 9 (glia-activating factor) | 2.2 | nd | nd | 3.0 | 3.7 | 3.0 | < 0.001 | – | – | < 0.001 | < 0.001 | < 0.001 | 24174570 |
| FGFR3 | 100,514,115 | FGFR3 | 2261 | fibroblast growth factor receptor 3 | −1.2 | −0.1 | −1.1 | −2.3 | – | − 0.6 | < 0.001 | 0.991 | 0.066 | < 0.001 | – | 0.048 | 20393170 |
| LOC100511475 | 100,511,475 | FXYD4 | 53,828 | FXYD domain containing ion transport regulator 4 | −4.9 | nd | −5.2 | −7.4 | −7.5 | – | < 0.001 | – | < 0.001 | < 0.001 | < 0.001 | – | 24174570 |
| LOC100513220 | 100,513,220 | GPR83 | 10,888 | G protein-coupled receptor 83 | −5.9 | nd | −7.5 | − 7.8 | −4.0 | – | < 0.001 | – | < 0.001 | < 0.001 | < 0.001 | – | 24174570 |
| HPGD | 100,156,186 | HPGD | 3248 | hydroxyprostaglandin dehydrogenase 15-(NAD) | −3.8 | −1.4 | −3.6 | −3.0 | −2.7 | – | < 0.001 | 0.005 | < 0.001 | < 0.001 | < 0.01 | – | 24695626 |
| LOC100739374 | 100,739,374 | IL24 | 11,009 | interleukin 24 | −2.8 | −1.4 | − 2.7 | −4.6 | −5.2 | −5.3 | < 0.001 | 0.254 | < 0.001 | < 0.001 | 0.024 | 0.033 | 24174570 |
| IRF1 | 396,611 | IRF1 | 3659 | interferon regulatory factor 1 | 0.6 | −0.1 | 0.4 | 0.4 | 0.5 | 2.9 | 0.115 | 0.890 | 0.397 | 0.087 | 0.188 | 0.003 | 24174570 |
| IRG1 | 100,524,951 | IRG1 | 730,249 | immunoresponsive 1 homolog (mouse) | 10.3 | 5.8 | 6.2 | 9.9 | 8.0 | – | < 0.001 | 0.000 | < 0.001 | < 0.001 | < 0.001 | – | 24174570 |
| OSTN | 100,049,691 | OSTN | 344,901 | osteocrin | nd | nd | nd | 10.3 | 12.4 | – | – | – | – | < 0.001 | < 0.001 | – | 24174570 |
| S100A9 | 100,127,489 | S100A9 | 6280 | S100 calcium binding protein A9 | 12.4 | 11.5 | 11.3 | 10.4 | 10.6 | 9.2 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 24174570 |
| SERPINB7 | 100,152,588 | SERPINB7 | 8710 | serpin peptidase inhibitor, clade B, member 7 | 10.4 | 7.9 | 6.2 | 10.3 | 8.9 | 5.4 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | 0.018 | 24174570 |
| SLCO2A1 | 100,144,510 | SLCO2A1 | 6578 | solute carrier organic anion transporter family member 2A1 | 1.0 | 0.4 | 2.3 | 0.5 | 3.0 | – | 0.011 | 0.960 | < 0.001 | 0.053 | < 0.001 | – | 24695625 |
| SLCO4C1 | 100,737,557 | SLCO4C1 | 353,189 | solute carrier organic anion transporter family member 4C1 | 1.6 | 0.2 | 1.3 | 2.3 | 2.6 | – | 0.007 | 0.978 | 0.174 | < 0.001 | < 0.05 | – | 27764917 |
| SLCO5A1 | 100,157,250 | SLCO5A1 | 81,796 | solute carrier organic anion transporter family member 5A1 | 8.4 | 4.9 | 5.9 | 6.4 | 9.2 | – | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.05 | – | 27764917 |
| SPP1 | 397,087 | SPP1 | 6696 | secreted phosphoprotein 1 | 4.1 | 1.6 | 3.2 | 2.4 | 2.5 | 3.2 | < 0.001 | 0.005 | < 0.001 | < 0.001 | 0.008 | 0.029 | 24174570 |
| LOC100738308 | 100,738,308 | STAT1 | 6772 | signal transducer and activator of transcription 1, 91 kDa | 1.6 | 0.2 | 0.8 | 1.4 | 1.2 | 2.3 | < 0.001 | 0.562 | 0.066 | < 0.001 | 0.001 | < 0.001 | 24174570 |
| STC1 | 100,125,345 | STC1 | 6781 | stanniocalcin 1 | −2.9 | −1.0 | −2.9 | 1.9 | 2.5 | 2.0 | < 0.001 | 0.384 | < 0.001 | < 0.001 | 0.101 | 0.017 | 24174570 |
Ssc: Sus scrofa; Hsa: Homo sapiens; P/C: pregnant vs. control; *for RNA-seq adjusted p-values; nd: not detectable