Fig. 4. (a) Confocal images and (b) TEM images of cytoplasmic vacuolization. A549R cells were incubated with OnIr1 (1 μM), OnIr2 (1 μM), OnIr3 (2 μM) and OnIr4 (2 μM) for 24 h. (c) Confocal images of plasma membrane blebbing. A549R cells were incubated with OnIr1 (2 μM), OnIr2 (2 μM), OnIr3 (3 μM) and OnIr4 (3 μM) for 24 h. Scale bar in confocal images: 10 μm.
