Fig. 2.

Locomotion profiles of zebrafish exposed to sertraline and JWXY capsule after reserpine treatment in the novel tank test. a Diagram of locomotion behaviour recorded by a camera from a dorsal view. Histogram revealing the locomotion behaviour of adult zebrafish by the b total distance travelled, c average velocity, d turn angle, e angular velocity and f meandering. Control: untreated AB strain zebrafish. Acute: acute treatment with reserpine for 20 min. Model: after acute treatment with reserpine, zebrafish were exposed to system water for 7 days to generate the depression model. Sertraline: after acute treatment with reserpine, zebrafish were exposed to sertraline for 7 days. JWXY: after acute treatment with reserpine, zebrafish were exposed to JWXY capsule for 7 days. The data are expressed as the mean ± S.E.M. and were analysed by one-way ANOVA followed by the Tukey post hoc test. Significance was defined as *p < 0.05, **p < 0.01