Figure 8.

Average Q_p frequency response for on-cell patches compared with subsequent whole-cell measures. A, On-cell Q_p with Boltzmann fits to data from individual frequencies. B, Frequency response in patches is low pass. C, D, Following patch rupture, Q_p increases (C) and frequency response extends (D). These data possibly signify that patch movements are constrained compared with whole-cell conditions, as previously suggested (Gale and Ashmore, 1997). Five millivolt peak AC stimulation. Patch responses were averaged 32 times.