Table 2.
Frequency, and intensity of adverse effects observed on 753 patients treated with MDT
Signs and Symptoms | Absent | Mild | Moderate | Severe | Total | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
N | % | N | % | N | % | N | % | N | % | ||
Skin pigmentation | 8298 | 78.3% | 1715 | 16.2% | 572 | 5.4% | 14 | 0.1% | 10599 | 100% | |
Xerosis | 8813 | 83.1% | 1444 | 13.6% | 297 | 2.8% | 46 | 0.4% | 10600 | 100% | |
Itch | 10252 | 96.7% | 280 | 2.6% | 56 | 0.5% | 10 | 0.1% | 10598 | 100% | |
Headache | 10278 | 97.0% | 287 | 2.7% | 34 | 0.3% | 1 | 0.0% | 10600 | 100% | |
Paleness | 10286 | 97.0% | 284 | 2.7% | 27 | 0.3% | 3 | 0.0% | 10600 | 100% | |
Fatigue | 10363 | 97.8% | 214 | 2.0% | 20 | 0.2% | 2 | 0.0% | 10599 | 100% | |
Myalgia | 10389 | 98.0% | 184 | 1.7% | 24 | 0.2% | 3 | 0.0% | 10600 | 100% | |
Anorexia | 10458 | 98.7% | 118 | 1.1% | 24 | 0.2% | 0 | 0.0% | 10600 | 100% | |
Dyspnea | 10475 | 98.8% | 109 | 1.0% | 16 | 0.2% | 0 | 0.0% | 10600 | 100% | |
Nausea | 10484 | 98.9% | 97 | 0.9% | 17 | 0.2% | 2 | 0.0% | 10600 | 100% | |
Abdominal pain | 10485 | 98.9% | 97 | 0.9% | 13 | 0.1% | 5 | 0.0% | 10600 | 100% | |
Weight loss | 10496 | 99.0% | 92 | 0.9% | 12 | 0.1% | 0 | 0.0% | 10600 | 100% | |
Fever | 10499 | 99.1% | 80 | 0.8% | 20 | 0.2% | 0 | 0.0% | 10599 | 100% | |
Diarrhea | 10524 | 99.3% | 61 | 0.6% | 15 | 0.1% | 0 | 0.0% | 10600 | 100% | |
Skin rash | 10538 | 99.4% | 41 | 0.4% | 18 | 0.2% | 1 | 0.0% | 10598 | 100% | |
Constipation | 10545 | 99.5% | 47 | 0.4% | 8 | 0.1% | 0 | 0.0% | 10600 | 100% | |
Erythroderma | 10548 | 99.5% | 26 | 0.2% | 21 | 0.2% | 5 | 0.0% | 10600 | 100% | |
Photodermatosis | 10552 | 99.5% | 23 | 0.2% | 24 | 0.2% | 1 | 0.0% | 10600 | 100% | |
Depression | 10553 | 99.6% | 37 | 0.3% | 8 | 0.1% | 0 | 0.0% | 10598 | 100% | |
Bleeding | 10562 | 99.6% | 27 | 0.3% | 11 | 0.1% | 0 | 0.0% | 10600 | 100% | |
Vomiting | 10563 | 99.7% | 26 | 0.2% | 10 | 0.1% | 1 | 0.0% | 10600 | 100% | |
Cyanosis | 10575 | 99.8% | 17 | 0.2% | 7 | 0.1% | 1 | 0.0% | 10600 | 100% | |
Jaundice | 10579 | 99.8% | 14 | 0.1% | 7 | 0.1% | 0 | 0.0% | 10600 | 100% |