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. 2018 Jun 14;11:82. doi: 10.1186/s13045-018-0625-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — exo-adipocyte-conditioned medium enhances tube formation of HUVECs. a HUVECs were incubated with exo-adipocyte-conditioned medium or adipocyte-conditioned medium for 48 h. The mRNA levels of Ang1, Flk1, Vash1, and TSP1 were evaluated by qRT-PCR. Results are mean ± SD (n = 3 for each group). b Compared with adipocyte-conditioned medium, exo-adipocyte-conditioned medium increased HUVEC tube formation in vitro. Scale bar, 100 μm. Right—representative photograph of tube formation. Left—calculations in three randomly selected fields. Results are mean ± SD (Student’s t test)